Indonesian police are expandinginvestigationWith the whole country Related to the deaths of over 200 children,ContaminatedofCough syrupThis incidentThese syrups are comparable to last year's Gambia and UzbekistantenThe deaths of children are related. World Health OrganizationalsoWe are collaborating with countries to investigate the global drug supply chain of this type of syrup.

At the end of last year, the police arrested and charged an Indonesian company witheightThese companies import and distribute raw materials to pharmaceutical manufacturers whose cough syrup has been found to contain toxic industrial grade chemicals,AndNot a legal component.

The investigation found that,Taking medicationThe cause of death in children may be that their cough syrup contains excessive ethylene glycol and Diethylene glycol. These two chemicals are mainly used in industrial fields such as antifreeze, but they can also serve as cheap substitutes for glycerol, a thickener for syrup based drugs, in the pharmaceutical industry. Previous studies have found that ethylene glycol and Diethylene glycol may cause Acute kidney injury.

Actually,As early asJuly 2022, GambiatenA child had kidney problems, which confused medical staff for a time. As the investigation deepens, it is found that these children have all taken the locally sold paracetamol syrup and after taking the medicationAttack within 3 to 5 days. The health department of Gambia has already recalled the relevant drugs.

On October 5, 2022, the World Health Organization targeted four types of colds produced by a pharmaceutical company in IndiadrugAnd cough syrup issued a product warning, because these products may be associated with Acute kidney injury, and may be associated with the death of children in Gambia.

In the product warning, WHO said that the laboratory analysis showed that the above syrup contained Diethylene glycol and ethylene glycol"Pollutant", and the content is "unacceptable", these toxic ingredients can lead to Acute kidney injury.

The senior management of the Indonesian Food and Drug Administration stated that the two local pharmaceutical companies involved used substandard raw materials, did not declare changes in drug composition, and some raw material usage exceeded the standard,In addition to revoking the licenses of these two enterprises, relevant criminal investigations are also ongoing.

The Indonesian Food and Drug Administration is also investigating the distributors of two involved pharmaceutical companies to confirm whether the relevant raw materials are also supplied to other pharmaceutical companies. However, one of the aforementioned enterprises has issued a statement denying the use of substandard raw materials in its products, while also claiming thatIn 2020, a change in drug composition was declared and approved. In addition, the company stated that its distributors did not provide any feedback on any issues with the product. Another company involved remained silent.

The police have filed charges against the four companies involved in the case, including pharmaceutical companies suspected of selling contaminated syrup Afi Farma, according to the police, provided chemicalsyes CV Samudera Chemical and its two distributors Tirta Buana Kemindo and Anugrah Perdana Gemilang,Investigators are currently inspecting drug regulatory agencies,confirmIs there any improper behavior.